The mechanism of forming an oxime from nucleophilic addition of a hydroxylamine to a ketone is taught early on in most courses of organic chemistry. Here I subject the first step of this reaction to form a tetrahedral intermediate to quantum mechanical scrutiny.
Tags:animation, energy difference, free energy, nucleophilic attack, Reaction Mechanism, text-book author, Tutorial material
Posted in Interesting chemistry, reaction mechanism | 5 Comments »
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