Results

Table 2. NMR Data
Compound
1H NMR (CDCl3/TMS)
d, J (Hz)
4
7.07 (dd, 1H, J=7.2 & 4.8, H-5), 7.10-7.38 (m, 5H, C6H5), 7.80 (dd, 1H, J=7.2 & 2.0, H-4), 8.56 (dd,1H, J=4.8 & 2.0, H-6)
6
2.38 (s, 3H, COMe), 7.26 (dd, 1H, J=7.2 & 4.8, H-5), 7.76 (s, 2H, NH2), 8.60 (dd, 1H, J=7.2 & 2.0, H-4), 8.68 (dd,1H, J=4.8 & 2.0, H-6)
8
3.92 (d, 2H, J=7.2, SCH3), 5.00-6.28 (m, 3H, CH=CH2), 7.02 (dd, 1H, J=7.2 & 4.8, H-5), 7.73 (dd, 1H, J=7.2 & 2.0, H-4), 8.32 (dd,1H, J=4.8 & 2.0, H-6)
9
2.18 (t,1H, J=2.4, CH), 4.01 (d, 2H, J=2.4, SCH2), 7.09 (dd, 1H, J=7.2 & 4.8, H-5), 7.80 (dd, 1H, J=7.2 & 2.0, H-4), 8.57 (dd,1H, J=4.8 & 2.0, H-6)
10
3.68 (s, 3H, CO2CH3), 4.00 (dd, 2H, J=7.0 & 1.2, SCH2), 6.00 (dd, 1H, J=14.4 & 1.2, CH=), 6.96 (m, 2H, H-5 & =CHCO2Me), 7.70 (dd, 1H, J=7.2 & 2.0, H-4), 8.52 (dd,1H, J=4.8 & 2.0, H-6)
11
1.32 (t, 3H, J=7.2, CH3), 4.28 (q, 2H, J=7.2, COCH2), 7.20 (s, 2H, NH2), 7.58 (dd, 1H, J=7.2 & 4.8, H-5), 8.30 (dd, 1H, J=7.2 & 2.0, H-4), 8.62 (dd,1H, J=4.8 & 2.0, H-6)
14
1.31 (t, 3H, J=7.2, CH3), 3.80 (s, 2H, COCH2CO2), 4.26 (q, 2H, J=7.2, COCH2), 6.90 (s, 2H, NH2), 7.31 (dd, 1H, J=7.2 & 4.8, H-5), 8.00 (dd, 1H, J=7.2 & 2.0, H-4), 8.70 (dd,1H, J=4.8 & 2.0, H-6)
15
5.91 (s, 1H, H), 7.55 (dd, 1H, J=7.2 & 4.8, H-5), 8.72 (m, 2H, H-4 & H-6), 13.50 (s, broad, 2H, NH & OH)